Manchester United - Nemanja Vidic could return to the starting line-up after a three-month absence as Jonny Evans is out with a hamstring problem, while Anders Lindegaard is available and will be hoping to oust David De Gea once again. We've been given no news on Wayne Rooney's illness but I've seen photos on Twitter of him training today so I assume he's fully recovered.
Liverpool - Luis Suarez returns from suspension but Jose Enrique could miss out with the hamstring injury he sustained during the first half at West Ham.
Arsenal - Olivier Giroud is fit and in the squad but Theo Walcott remains a doubt, so Alex Oxlade-Chamberlain could continue on the flank. Lauren Koscielny has recovered and could be involved but faces a battle with Per Mertesacker for the right to partner Thomas Vermaelen.
Manchester City - Captain Vincent Kompany has "only a 2% chance" of being fit according to Roberto Mancini due to the groin injury suffered against Manchester United, so either Kolo Toure or Joleon Lescott will start. Gareth Barry is serving a one-match ban for verbally abusing the referee in the same game so Javi Garcia should replace him. Remember we'll get the City line-up before the deadline as they kick-off at 12:45.
Tottenham - Gareth Bale is "very unlikely" to be fit according to AVB but there is better news for Spurs. Michael Dawson is back in training, as are long term absentees Scott Parker and Benoit Assou-Ekotto. All three "could" be involved, but my bet would be a place on the bench at best.
Norwich - Midfielders Wes Hoolahan and Alex Tettey are battling to return from injury but Steven Whittaker is a doubt due to a hip complaint.
West Brom - Steve Clarke has left us a rather cryptic and unhelpful message ahead of the weekend, stating "I won't reveal who, but we have a number of other injuries besides Foster, Yacob and Ridgewell", so I think your best best is to avoid West Brom entirely this weekend.
Stoke - Ryan Shotton serves a one-match ban so Andy Wilkinson will replace him. Charlie Adam is available after his own suspension.
Everton - Kevin Mirallas has suffered a recurrence of a hamstring injury so he'll be missing once again, while Tony Hibbert will be out for a while after surgery on a calf problem.
Swansea - Captain Ashley Williams is available after serving a one-match suspension but Pablo Hernandez is still out with a hamstring injury.
Newcastle - Gabriel Obertan could return but Hatem Ben Arfa is a major doubt with a reoccurance of his hamstring injury. Again, we'll get the line-up before the deadline as they kick-off at 12:45 but I wouldn't expect many of you to be picking Newcastle players this weekend.
QPR - Julio Cesar is fit again after a groin injury so he should return to take Robert Green's place. Harry Redknapp is still without Park Ji-sung who continues to struggle with a knee injury.
Fulham - Mahamadou Diarra remains so Chris Baird should continue in midfield. There are no other injuries to report for Martin Jol's men.
Aston Villa - Darren Bent will miss the Xmas and New Year period with a hamstring problem and Ron Vlaar remains sidelined with a calf injury, while Gabby Agbonlahor is also a doubt.
West Ham - In-form Mohamed Diame could be sidelined for up to 12 weeks with a hamstring injury which is a massive blow for the Hammers. George McCartney is a major doubt after suffering a knee injury in training.
Sunderland - Adam Johnson and Danny Rose are doubts but Steven Fletcher should be available despite an ongoing ankle problem.
Wigan - Maynor Figueroa returns from suspension but Gary Caldwell is set to miss out through injury and Ivan Ramis is also struggling. This should mean Piscu retains his starting spot.
Reading - Sean Morrison is with the ankle injury picked up in the first game of the double week. Jason Roberts, Hal Robson-Kanu, Pavel Pogrebnyak and Jimmy Kebe are doubtful, although a Monday night fixture gives them extra time to recover.
That's it for now but it's still quite early in the afternoon so I'll add any additional news as I hear / read about it.
My current Yahoo team is:
Lloris, Piscu, Vertonghen, Shorey, Rosicky, Sterling, Cazorla, Michu, Snodgrass, Suarez, Rooney
I had been considering downgrading Rooney to Carlos Tevez or Sergio Aguero to allow me to upgrade Rosicky, and / or Piscu, but this would leave me without a United striker for the stand-out match of the weekend.
Any thoughts on my predicament? How are things looking for you?