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Out: Fantasy-relevant players who have been confirmed out for the week, either through injury or suspension
Doubt: Players facing the dreaded fitness test, rotation concerns and those who are out of form/favor
In: The likeliest replacements for the Outs & Doubts or those returning from injury
Win: Fantasy player to watch / my hunch pick of the week
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Out: Santi Cazorla, Tomas Rosicky, Danny Welbeck, Jack Wilshere
Doubt: Alexis Sanchez, Francis Coquelin, Alex Oxlade-Chamberlain (rotation)
In: Mesut Ozil
Win: Mesut Ozil
The man in the middle of everything for the Gunners, his return is much needed for Arsenal. While it remains to be seen if Alexis will start or come off the bench, a return of both the big guns would be crucial for them as they face off with Chelsea on Sunday.
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Out: Jordan Amavi, Alan Hutton, Adama Traore
Doubt: Gabby Agbonlahor, Leandro Bacuna, Jack Grealish, Carlos Sanchez
In: Micah Richards (maybe)
Win: Mark Bunn
After a pair of terrific performances, the cheap Aston Villa keeper looks to have locked down the starting spot in net. They have a great matchups against West Brom this weekend, so he's a low cost, high ceiling option.
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Out: Tommy Elphick, Max Gradel, Tyrone Mings, Callum Wilson
Doubt: Matt Ritchie, Benik Afobe, Joshua King, Lewis Grabban
In: Juan Iturbe (maybe)
Win: Juan Iturbe
If Matt Ritchie or Benik Afobe (both of whom will be late fitness decisions) miss the match, look for the new acquisition from Roma to fill in for one of them. The young man has has shown flashes in limited action, but a start will give us a chance to see what he can really do. Afobe looks likely to start, but Ritchie is doubtful.
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Chelsea
Out: Radamel Falcao
Doubt: Pedro (rotation)
In: Eden Hazard
Win: Cesc Fabregas
It's been a long time since Fabregas was a viable fantasy option, but with Guus Hiddink showing his faith in John Obi Mikel and Nemanja Matic in the double pivot, the Spaniard has been pushed further up the pitch in the #10 role. Up against his former club, Fabregas has the chance to remind Arsenal and Chelsea fans alike that he's a valuable asset.
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Out: Yannick Bolasie, Dwight Gayle, Bakary Sako
Doubt: N/A
In: Mile Jedinak (maybe)
Win: Connor Wickham
Could a little bit of a confidence boost from Alan Pardew be enough for Wickham to rediscover some semblance of form? Sure, he's no Harry Kane, but maybe he'll get his act together for what promises to be a tough match.
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Out: Tyias Browning, Luke Garbutt
Doubt: Seamus Coleman, James McCarthy, Ramiro Funes Mori (rotation)
In: Bryan Oviedo
Win: Romelu Lukaku
While you can probably find merit in picking just about any Everton attacker for this match, Lukaku has been the most consistent performer for the Toffees and will be heavily involved in the attacking play against the Swans.
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Out: Jeffrey Schlupp, Andrej Kramaric
Doubt: Ritchie De Laet
In: N/A
Win: Jamie Vardy
Claudio Ranieri has confirmed that Vardy is getting back to his best after minor groin surgery, and with the news that Riyad Mahrez will no longer be on penalties, Vardy should be the beneficiary. Stoke present a challenge, but could offer the striker a way to get back into the incredible goalscoring form from earlier in the season.
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Liverpool
Out: Philippe Coutinho, Joe Gomez, Danny Ings, Dejan Lovren, Divock Origi, Martin Skrtel, Daniel Sturridge
Doubt: Jon Flanagan, Adam Lallana, Christian Benteke (form)
In: Jordon Ibe
Win: Jordan Henderson
Liverpool's captain has been integral to their success this season, and when he's been fit he's been among the most productive midfielders in the league, especially in fantasy formats that award points for additional scoring metrics than the official game. With Liverpool's recent record against Norwich, expect Henderson to provide some sort of attacking return.
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Out: Aleksandar Kolarov, Vincent Kompany, Samir Nasri, Wilfried Bony, Eliaquim Mangala
Doubt: Pablo Zabaleta (rotation)
In: Gael Clichy
Win: Gael Clichy
Since most people are well aware of the fact that Sergio Aguero is pretty much a permanent Win any time he's fit, let's focus on the French fullback who will be standing in for Kolarov this weekend. Dirt cheap in Fantrax, the former Arsenal left back represents great potential value for investment this weekend.
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Out: Ashley Young, Michael Carrick, Phil Jones, Bastian Schweinsteiger, Marcos Rojo, Luke Shaw, Antonio Valencia
Doubt: Juan Mata (selection)
In: Cameron Borthwick-Jackson, Adnan Januzaj (maybe)
Win: Wayne Rooney
It's taken more than half of the season, but Louis van Gaal has finally figured out that Rooney is a striker. Since he's been deployed up top, he's been in excellent form and given his streaky goalscoring history, it's hard to bet against him making it three straight games with a goal.
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Newcastle
Out: Vurnon Anita, Papiss Cisse, Jack Colback, Paul Dummett, Siem De Jong, Tim Krul, Cheikh Tiote
Doubt: N/A
In: Jamaal Lascelles, Henri Saivet
Win: Jonjo Shelvey
Wijnaldum is the form player, but all of his goals have come at home. Shelvey had an excellent debut for the Magpies, and while he didn't score or assist, he was central to the best of Newcastle's attacking play. Expect that to continue against Watford.
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Out: Gary O'Neil (suspended)
Doubt: Diumerci Mbokani (rotation), Cameron Jerome (selection)
In: Steven Naismith
Win: Steven Naismith
The former Everton striker wasn't getting the playtime he deserved on Merseyside, but was always a threat when he was on the pitch. Expect him to be a nuisance to the Liverpool back line.
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Out: Florin Gardos, Jay Rodriguez, Maarten Stekelenburg
Doubt: Graziano Pelle, Dusan Tadic (selection)
In: Charlie Austin (maybe)
Win: Sadio Mane
It wasn't too long ago that it looked like Mane was destined for Man United. He's got his chance to audition directly in front of them with an eye toward a summer move, and has the quality to make stand-in left back Borthwick-Jackson look silly if he's on form.
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Out: Geoff Cameron, Shay Given
Doubt: Marko Arnautovic, Xherdan Shaqiri
In: Jonathan Walters (maybe)
Win: Bojan Krkic
With injury doubts surrounding Stoke's best attacking threats, Bojan is the most assured of starting and should have plenty of chances to make an impact for the Potters. He has formed a good partnership with Joselu recently and will be eager to build on that.
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Out: Younes Kaboul, Sebastian Larsson
Doubt: Jordan Pickford, Jan Kirchhoff (form)
In: Vito Mannone
Win: Patrick van Aanholt
PVA has been in exceptional form lately, especially in the attack. Pair his attacking contributions with a potential clean sheet and you've got a recipe for success.
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Out: Franck Tabanou (left club)
Doubt: Bafetimbi Gomis (selection), Kyle Naughton (rotation)
In: Angel Rangel (maybe)
Win: Gylfi Sigurdsson
A change in formation has seen Swansea performing a bit better of late, and there are signs that their attacking midfielder could be rediscovering his best form. If the Swans are going to get anything out of Everton, expect Sigurdsson to be involved.
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Out: Clinton N'Jie, Ryan Mason, Alex Pritchard
Doubt: Kieran Trippier, Heung-Min Son, Ben Davies (all rotation)
In: Danny Rose, Kyle Walker
Win: Harry Kane
Alan Pardew's comments in reference to Connor Wickham could also backfire and have the effect of spurring Kane to prove just how much better a player he is. Watch out, Eagles.
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Out: Alessandro Diamanti (left club)
Doubt: Sebastian Prodl (selection), Valon Behrami (rotation)
In: Nordin Amrabat (maybe)
Win: Nathan Ake
It's been a long while since Watford looked like a top-half team. Their success in the early stages of the season was built on their defensive strength at home, and they could rediscover that this weekend with everyone fit and some strong competition for Heurelho Gomes with the signing of Costel Pantilimon. Ake has the attacking potential to offset the loss of a clean sheet, but it would certainly be a nice bonus.
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Out: James Morrison
Doubt: Jonas Olsson, Chris Brunt, Darren Fletcher
In: Stephane Sessegnon
Win: Jonny Evans
The former Red Devils defender has been a solid fantasy pick since nailing down a starting role for the Baggies. Tony Pulis has fielded the versatile player at center back and holding midfielder, but he looks likely to play at left back this weekend and could provide some additional attacking potential to his defensive capabilities.
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Out: Manuel Lanzini, Diafra Sakho, Andy Carroll, Mauro Zarate (left club)
Doubt: James Tomkins, James Collins (rotation)
In: Sam Byram (maybe), Victor Moses, Winston Reid (maybe)
Win: Dimitry Payet
It's difficult to bet on anyone else making a huge impact against Man City, though you could argue the merits of Michail Antonio or Victor Moses on the wings. It's Payet's extra bit of potential for magic that earns him this spot.