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A look at which players may be missing from your potential fantasy line-ups due to suspension, injury or rotation and returning players who may make an impact.
Out: Fantasy-relevant players who have been confirmed out for the week, either through injury or suspension
Doubt: Players facing the dreaded fitness test, rotation concerns and those who are out of form/favor
In: The likeliest replacements for the Outs & Doubts
Win: Fantasy player to watch / my hunch pick of the week
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Out: Oxlade-Chamberlain (match fitness, 7 May)
Doubt: Cazorla (match fitness), Rosicky (match fitness)
In: N/A
Win: Alexis Sanchez
The Chilean will look to influence Arsenal again in a must win match against Norwich City to hold their place in the UEFA Champions League next season.
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Out: Richardson (calf, 7 May), Amavi (knee, unknown)
Win: Jordan Ayew
Already playing for pride, Ayew will have to be the key player against Watford, despite relegation.
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Out: Mings (knee, Sep), Arter (calf,unknown), Smith (hernia, unknown)
Doubt: Gradel (hip)
In: N/A
Win: Joshua King
A tricky Everton side is always hard to beat, so therefore, all the pressure might go Josh King in this one and it might be good.
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Out: Rémy (groin, Aug), Zouma (knee, Oct)
Doubt: Cahill (illness), Terry (ankle)
In: N/A
Win: Diego Costa
Just awaiting the end of the season, the Spaniard will have to be on top form to put the final nail on the coffin of Spurs' Premier League dream.
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Out: Hangeland (knee, May), Appiah (knee, Aug), Anderson (leg, Aug), Chamakh (groin, Aug)
Doubt: Zaha
In: N/A
Win: Yohan Cabaye
Crystal Palace won their first game against Newcastle since 1998, can they do the double this time and put Newcastle one step closer to relegation?
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Out: Barry (groin, 7 May), Browning (knee, Jun), Coleman, Jagielka (both hamstring, unknown), Funes Mori
Doubt: N/A
In: N/A
Win: Romelu Lukaku
The Belgian will have to be a scoring machine against Bournemouth.
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Out: Vardy
Doubt: N/A
In: N/A
Win: Riyad Mahrez
Claudio Ranieri's men were 5,000 to 1 at the start of the season to win the Premier League. They are now 90 minutes and three points away from securing their maiden title. No Jamie Vardy? Upstep, Riyad Mahrez, who continues to demonstrate time and time again why he is the player of the year.
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Out: Henderson (knee, 15 May), Can (ankle), Gomez, Ings (both knee, all Jun), Origi (ankle), Rossiter (hamstring, both unknown)
Doubt: Coutinho
In: N/A
Win: Daniel Sturridge
Jurgen Klopp's side will have to recover from their Europa League loss and have all attention on that next Thursday but everything is on the line and preparation will be key, against Swansea is no different.
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Out: Touré (thigh, 8 May), Silva (hamstring, unknown)
Doubt: N/A
In: Jesus Navas
Win: Sergio Aguero
The Argentine will not only has to be focused against Real Madrid in a few days in the UCL semifinals, but will have to demonstrate that again, this time against Southampton.
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Out: Shaw (leg, 21 May), Keane (pelvis), Schweinsteiger (knee, both unknown)
Doubt: Januzaj (match fitness)
In: N/A
Win: Marcus Rashford
The young English striker might be the one that will ruin Leicester City's Premier League dream for this week.
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Newcastle
Out: Janmaat (hand, 7 May), Elliot (knee, Jul), Haïdara (knee, Jul), Krul (knee, Aug), Coloccini (calf, unknown)
Doubt: N/A
In: N/A
Win: Georginio Wijnaldum
Bring on Georginio Wijnaldum, the man who can demonstrate to Newcastle that they deserve to play another season in the Premier League.
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Out: Klose (knee, 15 May), Tettey (ankle), Wisdom (knee, both unknown)
Doubt: N/A
In: N/A
Win: Nathan Redmond
Nathan Redmond has the chance to probably surprise everyone and get a fantastic result against Arsenal.
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Out: Gardos (knee, unknown)
Doubt: Austin (knee)
In: N/A
Win: Graziano Pelle
Ronald Koeman's side is looking to unfocus Manchester City and the Italian striker might be the man to do it.
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Out: Johnson (knee, 7 May), Butland (ankle, Jul), Afellay (knee, Jan), Given (groin, unknown)
Doubt: Shaqiri (hamstring), Walters (knee), Wilson (knee)
In: N/A
Win: Marko Arnautović
The Austrian will look to influence their side to three points and send Sunderland to relegation.
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Out: N/A
Doubt: N/A
In: N/A
Win: Jermain Defoe
Defoe has been in excellent form since January and could be key to the Black Cats' survival.
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Out: Fer (hamstring, unknown), Paloschi (hamstring, unknown)
Doubt: N/A
In: N/A
Win: Bafetimbi Gomis
Gomis has been a revelation this season, and should cause plenty of problems for the Reds, as they try to lose their opponent's focus ahead of their Europa League tie.
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Out: Bentaleb (knee, May), Alli
Doubt: N/A
In: Mousa Dembele
Win: Harry Kane
Who else can continue Chelsea's woes of this season? Harry Kane of course.
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Out: Capoue (knee, unknown)
Doubt: N/A
In: N/A
Win: Heurelho Gomes
Gomes has been excellent in goal, and will need to be again here, this time against Aston Villa.
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Out: Morrison (ankle, 7 May), Brunt (knee, Oct), Pritchard (hip, unknown)
Doubt: Berahino (ankle), Foster (ankle)
In: N/A
Win: Salomon Rondon
The Venezuelan striker will definitely be a huge factor to ruin West Ham United's dream of reaching European competitions.
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Out: Jenkinson (knee, Nov)
Doubt:N/A
In: N/A
Win: Dimitri Payet
Payet has been the star this season and he might be the man to help the Hammers to a European competition.
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