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Out: Fantasy-relevant players who have been confirmed out for the week, either through injury or suspension
Doubt: Players facing the dreaded fitness test, rotation concerns and those who are out of form/favor
In: The likeliest replacements for the Outs & Doubts or those returning from injury
Win: Fantasy player to watch / my hunch pick of the week
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Out: Alex Oxlade-Chamberlain, Jack Wilshere
Doubt: Aaron Ramsey, Mathieu Flamini, David Ospina (selection)
In: Petr Cech
Win: Alexis Sanchez
The Chilean has rounded back into form lately, and looks set to be the Gunners' most dangerous attacking player for the run-in.
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Out: Alan Hutton (suspended), Jordan Amavi
Doubt: Ciaran Clark
In: Leandro Bacuna, Jack Grealish (maybe)
Win: Rudy Gestede
With uncertainty elsewhere in the Villa attack and the defense hardly worth considering this season, the big man is the go-to if you're thinking of buying in.
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Out: Benik Afobe, Harry Arter, Junior Stanislas
Doubt: Adam Smith
In: Lewis Grabban, Josh King, Tommy Elphick, Eunan O'Kane
Win: Max Gradel
Gradel is a fantasy favorite, particularly in formats where he can earn peripheral "phantom" points. He'll be a handful for Villa's stand-in right back.
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Out: Diego Costa (suspended), Eden Hazard, Loic Remy, Nemanja Matic, John Terry
Doubt: Gary Cahill
In: Willian, Alexandre Pato
Win: Branislav Ivanovic
The defending champions are experiencing a bit of an injury crisis at the moment, but the veteran defender will play and has a good shot at contributing positive returns on both sides of the game.
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Out: James McArthur
Doubt: Emmanuel Adebayor, Joe Ledley (selection)
In: Yohan Cabaye, Connor Wickham
Win: Yannick Bolasie
The winger is a special talent when he's on his game, and he'll need to be to help the Eagles avoid slipping closer to the relegation zone in a crucial match against Norwich.
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Out: N/A
Doubt: Darron Gibson, Leon Osman, Tom Cleverley (selection)
In: Gareth Barry
Win: Ross Barkley
The return of Gareth Barry from suspension should allow Barkley to push further up in the attack to his preferred role behind Romelu Lukaku. After a few quiet outings, he should return to his best.
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Out: N/A
Doubt: N/A
In: N/A
Win: Christian Fuchs
Claudio Ranieri has his preferred lineup established, and with no new injury concerns will likely stick with the same lineup. Fuchs has been fantastically consistent and is one of the few Foxes who can offer both attacking and defending potential every match.
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Out: Jordan Henderson, Emre Can (suspended), Christian Benteke, Lucas
Doubt: Alberto Moreno (rotation)
In: Roberto Firmino, Joe Allen, Daniel Sturridge, Jon Flanagan (maybe)
Win: Philippe Coutinho
Firmino's return should free up additional space for Coutinho to work in. The little Brazilian didn't have the greatest night against Dortmund, but we probably wouldn't be saying that had his goalbound shot not been saved by Roman Weidenfeller.
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Out: Raheem Sterling, David Silva, Vincent Kompany
Doubt: Yaya Toure, Gael Clichy (rotation), Bacary Sagna (rotation)
In: Jesus Navas, Samir Nasri, Joe Hart
Win: Sergio Aguero
The de facto pick, yes, but with so many other question marks in the squad it's difficult to pick anyone else. Perhaps the last week the Argentine should be an automatic selection in your team before we get into the double weeks.
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Out: Wayne Rooney, Bastian Schweinsteiger
Doubt: Daley Blind
In: Timothy Fosu-Mensah (maybe)
Win: Anthony Martial
Breaking down the league's best defensive unit won't be easy, but Martial has shown he has the quality to beat his man on the dribble or put away a chance.
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Out: Fabricio Coloccini, Rob Elliott, Jack Colback (suspended)
Doubt: Papiss Cisse (rotation)
In: Paul Dummett, Aleksandar Mitrovic
Win: Andros Townsend
With the Magpies faltering, they may be more eager to take some shots out of desperation. Nobody loves a long-range pop more than the former Spurs wide man. Expect lots of shots, with the potential for one to squeeze in.
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Out: Alexander Tettey
Doubt: Andre Wisdom
In: Russell Martin
Win: Steven Naismith
We saw early in the season when he was still an Everton player that Naismith can be unplayable when given his chance. He should be utilized in the number 10 role again and faces the utterly hapless Crystal Palace team.
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Out: Steven Davis
Doubt:
In: Shane Long, Dusan Tadic
Win: Fraser Forster
As mentioned above, I expect Newcastle to take quite a few shots as they push for survival. Forster is a brick wall more often than not and could have a big day, especially if he can record yet another clean sheet for the Saints.
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Out: Jack Butland, Glen Johnson, Marc Wilson
Doubt: Marc Muniesa (rotation), Marko Arnautovic, Glenn Whelan
In: Ryan Shawcross, Xherdan Shaqiri, Geoff Cameron
Win: Xherdan Shaqiri
Liverpool will be operating on somewhat weary legs after their midweek exertions against Dortmund, and Shaqiri will face off against the left back. Even if Flanagan does replace one of the fullbacks for the Reds, his fresh legs will be patrolling the right flank. The Swiss winger could find some joy out wide.
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Out: Duncan Watmore, Emmanuel Eboue
Doubt: N/A
In: N/A
Win: Fabio Borini
It's crunch time again for Sunderland. Can the Italian striker be their savior yet again? This is historically about the time he gets a goal streak going.
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Out: N/A
Doubt: Jordi Amat, Leon Britton
In: Ki Sung-yueng
Win: Gylfi Sigurdsson
The Icelendic midfielder has been in excellent form since Francesco Guidolin took the helm. His set piece quality alone should be enough to put him in your considerations, especially against a less-than-full-strength Chelsea defense.
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Out: Nabil Bentaleb
Doubt: Jan Vertonghen, Son Heung-Min (rotation)
In: Erik Lamela
Win: Harry Kane
Yet again pushing for the Golden Boot. The Hurrikane continues to blow through opposition defenses.
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Out: N/A
Doubt: Mario Suarez, Almen Abdi (both rotation)
In: Valon Behrami, Nordin Amrabat
Win: Odion Ighalo
He's gone completely off the boil since the start of 2016, but I like Ighalo's chances to get back on the score sheet at home against Everton. Call it a hunch.
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Out: Chris Brunt, James Morrison
Doubt: Sandro (rotation)
In: Stephane Sessegnon
Win: Craig Gardner
In what looks like a very tough match for the Baggies, it's not easy to pick a stand-out for investment, but Gardner has the set-piece quality to trouble even the best defensive teams and could exploit the Kompany-less City back line.
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Out: Sam Byram, James Collins
Doubt: N/A
In: James Tomkins
Win: Dimitri Payet
The Frenchman is making a late push to be included in the player of the year conversation. If he hadn't been injured for a long period of time, he may have had an even stronger case. If anyone is going to trouble a resurgent Arsenal side, it's him.
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Has this injury news affected your plans for this weekend? Are there any slight doubts you're still considering for your team? Share your thoughts and questions in the comments!